Somatic Mutation Testing

Testing for the presence of cancer requires the utmost personal care and consideration. Somatic mutation testing is enormously beneficial for improving the prognosis and the quality of life of cancer-affected patients. Our team of hereditary and somatic cancer experts will support you during every step of the process.

Our portfolio for somatic mutation testing

Identifying Somatic Mutations for Tumor Profiling

Every cancer cell can evolve its own pattern of mutated genes.

Each person's cancer, and even parts of a single tumor, can become completely unique. This has implications with respect to diagnosis, prognosis and treatment response. The presence of recurrent somatic mutations allows us to create a detailed molecular fingerprint of the tumor and to identify important tumor subtypes.

How Can Somatic Genetic Testing Help Patient Care?

Somatic mutation analysis is a standard of practice for tumors in order to identify therapeutic sensitizing and resistance mutations. This allows a finer assessment of the diagnosis and prognosis and targeted therapies directed towards the individual patients tumor profile.

What Do We Know About Somatic Mutations?

Cancer is one of the leading causes of morbidity and mortality worldwide. Cancer can be the result of a genetic predisposition that is inherited from family members (germline (hereditary) gene mutation) or it can be the result of the acquired mutations accumulated during a lifetime (somatic (acquired) mutation).

Unlike regular cells, cancer cells do not experience physiological elimination of “programmed cell death” or “apoptosis”; instead they continue to grow and divide. Tumor cells show uncontrolled proliferation if there are mutations in the genes involved in cell division .

Somatic Mutation Testing for Myeloid Tumors

Genetic testing of myeloid tumors can help you make accurate diagnoses, provide prognoses, choose appropriate therapy and counsel patients

Learn more

Note

Hotspot targeted mutation testing is unavailable in the US for the following mutations: BRAF c.1799T>A p.V600E, EGFR c.2573T>G, p.L858R, KRAS c.35G>A, p.G12D, KRAS c.38G>A, p.G13D, KRAS c.35G>T p.G12V, NRAS c.181C>A p.Q61K, NRAS c.34G>T, p.G12C, NRAS c.35G>A, p.G12D, NRAS c.182A>G, p.Q61R.

Resources

Downloads

CENTOGENE Productsheet Solid Tumor Panel English

Solid Tumor Panel – Product Sheet

Providing knowledge to battle cancer

CENTOGENE Myeloid Productsheet English PDF

Myeloid Tumor Panel – Product Sheet

The targeted approach to detecting myeloid malignancies

Scientific Publications

COVID-19 and Parkinson’s Disease

As one of the company’s priority diseases, CENTOGENE is continuously carrying out research into the causes of Parkinson’s disease (PD). A recurrent observation has been a temporal link of the […]

Loading...

Related Webinars

Regreso seguro a la normalidad: como realizar pruebas preventivas de Coronavirus en su organización

Descubre los conocimientos más recientes sobre la importancia de las pruebas preventivas de coronavirus a gran escala y el plan de CENTOGENE para implementarlo con éxito en su organización.

Loading...

Back to Business: How to Deploy Preventative Coronavirus Testing at Your Organization

Join us as we share the latest insights into the importance of large-scale, preventative coronavirus testing and our blueprint for successfully deploying it at your organization.

Loading...

La nueva normalidad en la pandemia de SARS-CoV-2: contribuciones de un laboratorio de diagnóstico de alta complejidad

Mira nuestro webinar, donde Pilar Guatibonza, MD, nos habla de cómo CENTOGENE ha establecido con éxito un laboratorio para la detección de SARS-CoV-2 y ha desarrollado una prueba de alta calidad y […]

Loading...

Get in Touch With Our Customer Support

Our consultation service is available in several languages.

+49 (0) 381 80 113 - 416

Mon. – Fri. 7 a.m. – 6:30 p.m. CET
Sat. 8 a.m. – 12 p.m. CET

Contact Us

For our US Partners:

+1 (617) 580 - 2102

Mon. – Fri. 9 a.m. – 5:30 p.m. EST


Contact Us