Our CentoCloud Diagnostic Portfolio

The Twist Alliance CNTG Exome design delivers the ideal quality and performance with outstanding clinical coverage and unmatched clinical diagnostic power in a single test. Coupling insights from our extensive Bio/Databank in rare diseases with superior omics technology, patients and physicians benefit from a unique approach that increases diagnostic yield up to 20 % compared to standard WES via enhanced coverage of the exome, full mitochondrial genome, and known medically-associated genes and variants.^1-9

CentoCloud Genome uses already available Illumina library kits and offers the most comprehensive one-step solution with the highest diagnostic yield. CentoCloud Genome offers unparalleled genome coverage and captures one of the most extensive ranges of disease-causing genetic variants in a single test. Our WGS solution is a highly effective diagnostic tool – delivering high diagnostic yields across a variety of rare genetic conditions. CentoGenome is especially valuable in patients for whom previous WES produced negative results, with a recent study showing its ability to solve up to 30% of WES negative cases.⁵

When choosing one of our Twist Alliance CNTG powered panels, their quality, our design, and our tailored bioinformatics service delivers the ideal quality and performance from the world leader and trusted partner in rare disease diagnostics with outstanding clinical coverage and unmatched clinical diagnostic power. Striving for a faster diagnosis at lower overall costs.

All panel designs benefit from CENTOGENE’s more than 16 years of rare disease diagnostic experience and AI-supported clinical interpretation and medical reporting. Validated extensively in CENTOGENE’s own diagnostic laboratory, the designs are based on scientific & clinical knowledge from public repositories (ClinVar, OMIM^®), proprietary databases (HGMD^® Professional) and unique insights from CENTOGENE’s own Biodatabank.

When choosing one of our Twist Alliance CNTG powered panels, their quality, our design, and our tailored bioinformatics service delivers the ideal quality and performance from the world leader and trusted partner in rare disease diagnostics with outstanding clinical coverage and unmatched clinical diagnostic power. Striving for a faster diagnosis at lower overall costs.

All panel designs benefit from CENTOGENE’s more than 16 years of rare disease diagnostic experience and AI-supported clinical interpretation and medical reporting. Validated extensively in CENTOGENE’s own diagnostic laboratory, the designs are based on scientific & clinical knowledge from public repositories (ClinVar, OMIM^®), proprietary databases (HGMD^® Professional) and unique insights from CENTOGENE’s own Biodatabank.